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Early Resuscitation in Paediatric Sepsis: A pilot study

Quick facts

Principal investigator:
Dr Christa Bell
Team members:
Ms Amanda Harley, Dr Megan King, A/Prof Luregn Schlapbach, Dr Shane George, Prof Gerben Keijzers, A/Prof Kristen Gibbons, Dr Paula Lister, Prof Rinaldo Bellomo, and A/Prof Andreas Schibler
Project commenced:

Sepsis accounts for more than 1 million annual childhood deaths globally. In Australia, more than 50 children die each year from this disease, and many children that survive contend with long-term disabilities. Indigenous children are particularly vulnerable.

Queensland is implementing a Statewide Paediatric Sepsis Collaborative which mandates sepsis treatment packages. To this point, the evidence for sepsis treatment other than antibiotics is limited.

This study is one of the largest randomized-controlled trials on early resuscitation of children with sepsis, and will test two interventions with the greatest promise to improve patient outcomes. The study will capture functional outcomes and quality of life, consumer engagement, and sepsis-related costs.


“The study is nested within a clearly defined clinical pathway, ensuring that findings can be rapidly translated into guidelines and change practice. The wide dissemination of findings will increase awareness of sepsis in the community and help save lives.”

—Dr Christa Bell

Grants Awarded

Gold Coast Health and Gold Coast Hospital Foundation Research Grants Scheme

Emergency Medicine Foundation

Last updated 19 Aug 2020