ARISE FLUIDS Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In emergency Department Sepsis
Quick facts
Dr Katya May, Ms Emma Hall, Dr Richard Pellatt, Dr James Winearls, Dr James McCollough, Ms Mandy Tallot and Ms Maimoonbe Gough
This study is conducted in collaboration with the Australian and New Zealand Intensive Care Research Centre (ANZIC-RC). It is endorsed by the Australian and New Zealand Intensive Care Society Clinical Trials Group & the Australian College for Emergency Medicine Clinical Trials Network.
The aim of this study is to compare the effect of a strategy of restricted fluids and early introduction of vasopressors to a strategy which involves a larger initial volume of IV fluid and later vasopressor administration if required, for haemodynamic resuscitation of patients with early septic shock.
The objective is to provide robust evidence for clinicians regarding the optimal approach to early haemodynamic resuscitation in septic shock to improve patient-centred clinical outcomes.
