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Does distance to hospital affect emergency department presentations and hospital length of stay among chronic obstructive pulmonary disease patients?. Internal Medicine Journal

Rana, R., Gow, J., Moloney, C., King, A., Keijzers, G., Beccaria, G. and Mullens, A., 2022. Does distance to hospital affect emergency department presentations and hospital length of stay among chronic obstructive pulmonary disease patients?. Internal Medicine Journal, 52(3), pp.403-410. https://doi.org/10.1111/imj.15014
 

Clinical presentation and assessment of older patients presenting with headache to emergency departments: A multicentre observational study. Australasian Journal on Ageing,

Beck, S., Kinnear, F.B., Maree Kelly, A., Chu, K.H., Sen Kuan, W., Keijzers, G., Body, R., Karamercan, M.A., Klim, S., Wijeratne, T. and Kamona, S., 2022. Clinical presentation and assessment of older patients presenting with headache to emergency departments: A multicentre observational study. Australasian Journal on Ageing, 41(1), pp.126-137. 

Pregabalin vs placebo to prevent chronic pain after whiplash injury in at-risk individuals: results of a feasibility study for a large randomised controlled trial. Pain,

Nikles, J., Keijzers, G., Mitchell, G., Farrell, S.F., Perez, S., Schug, S., Ware, R.S., McLean, S.A., Connelly, L.B. and Sterling, M., 2022. Pregabalin vs placebo to prevent chronic pain after whiplash injury in at-risk individuals: results of a feasibility study for a large randomised controlled trial. Pain, 163(2), pp.e274-e284. doi: 10.1097/j.pain.0000000000002362

FEISTY II: Blood clot treatments for patients with severe bleeding compared in new phase of clinical trial

The Fibrinogen Early In Severe Trauma Study II, known as FEISTY II has begun at Gold Coast Health.

FEISTY II represents a vital step forward in the quest for improved trauma care and builds on the success of FEISTY I. The study has garnered international attention for its efforts to optimise use of blood products in severely bleeding trauma patients.


Vasopressor Infusion via Peripheral vs Central Access in emergency department patients with shock – The VIPCA RCT

Quick facts

Principal investigator:

Dr Thomas Holland

Team members:
Project commenced:
2022

Shock is an umbrella description for poor blood supply to vital organs and can lead to multi-organ failure and death. Emergency department (ED) patients with shock are amongst the sickest, with 1/3 being admitted to an intensive care unit (ICU). Low blood pressure, a key feature of shock which causes the poor blood supply to vital organs, can be treated with medications called vasopressors. Vasopressors traditionally have been given through a so-called 'central line'. Central lines are invasive to insert and require skill, and the actual insertion can lead to complications. More evidence has emerged that so-called peripheral lines (aka 'drip') are safe for vasopressor infusion. Randomised controlled trials (RCT) to compare the two strategies will provide high quality data to inform clinicians as to which approach is best for patients, staff and the healthcare budget. We propose a feasibility RCT to test processes and inform a large phase-III RCT to definitively answer this question. We expect that the impacts of this RCT will include: *Potentially improved patient outcomes from avoiding risks of central lines * Improved patient experience from avoiding having central line insertion * Broad applicability to low-resource settings such as rural/regional/remote areas and low-income countries *Cost savings for healthcare services through reduced use of central lines

Grants Awarded

Emergency Medicine Foundation
$38,766


Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis

Macdonald, S., Bosio, E., Keijzers, G., Burrows, S., Hibbs, M., O’Donoghue, H., Taylor, D., Mukherjee, A., Kinnear, F., Smart, L. and Ascencio-Lane, J.C., 2022. Effect of intravenous fluid volume on biomarkers of endothelial glycocalyx shedding and inflammation during initial resuscitation of sepsis. 
 

The impact of antibiotics on clinical response over time in uncomplicated cellulitis: a systematic review and meta-analysis

Yadav, K., Krzyzaniak, N., Alexander, C., Scott, A.M., Clark, J., Glasziou, P. and Keijzers, G., 2022. The impact of antibiotics on clinical response over time in uncomplicated cellulitis: a systematic review and meta-analysis. Infection, pp.1-13.  
 

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