Renal pelvicalyceal rupture secondary to extraperitoneal pelvic packing (EPP) in the unsIntable trauma patient
Mansbridge, M. M., Latif, E. R., Lamdark, L. T., & Wullschleger, M. (2018). Case Reports, 2018, bcr-2018.
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Establishing a successful perioperative geriatric service in an Australian acute surgical unit
Styan, L., Murphy, S., Fleury, A., McGowan, B., & Wullschleger, M. (2018). ANZ journal of surgery, 88(6), 607-611.
Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients with Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial
Walters, K., Wake, E., Campbell, D., Wullschleger, M., Chalasani, A., Ho, D., ... & Winearls, J. (2018). Australian Critical Care, 31(2), 116.
Critical evaluation of a targeted point of care ROTEM guided coagulation and haemostasis management programme in severe trauma
Walters, K., Wake, E., Campbell, D., Wullschleger, M., Chalasani, A., Ho, D., ... & Winearls, J. (2018). Australian Critical Care, 31(2), 116.
Fibrinogen Early In Severe Trauma studY II (FEISTY II)
Quick facts
Principal investigator:
Dr Don Campbell
Team members:
Dr James Winearls
Dr Glenn Ryan
Dr Jeff Presneill
Dr Michael Reade
Dr Wayne Dwyer
Prof Gerben Keijzers
Prof Dev Mitra
Prof John Fraser
Dr Glenn Ryan
Dr Jeff Presneill
Dr Michael Reade
Dr Wayne Dwyer
Prof Gerben Keijzers
Prof Dev Mitra
Prof John Fraser
Project commenced:
2018
In a severe trauma, major bleeding or haemorrhaging is associated significant morbidity and mortality. Haemorrhage can be compounded by Trauma Induced Coagulopathy. It is postulated that early replacement of low fibrinogen levels may reduce haemorrhage and improve outcomes. Fibrinogen concentrate is an alternative way to replace fibrinogen.
In the FEISTY pilot trial, we demonstrated that a guided fibrinogen replacement strategy utilising either fibrinogen concentrate or cryoprecipitate is feasible. We found that fibrinogen concentrate was significantly faster to administer. The follow-on FEISTY II Trial will evaluate relevant patient-centred endpoints of a guided dose of FC Vs cryoprecipitate in traumatic haemorrhage. This larger study builds on the success of FEISTY to include multiple trauma centres in Australia and overseas.
Grants Awarded
Fibrinogen Early In Severe Trauma studY II (FEISTY II)
$100,000
