Pregabalin vs placebo to prevent chronic pain after whiplash injury in at-risk individuals: results of a feasibility study for a large randomised controlled trial.

Nikles, J., Keijzers, G., Mitchell, G., Farrell, S.F., Perez, S., Schug, S., Ware, R.S., McLean, S.A., Connelly, L.B. and Sterling, M., 2022. Pregabalin vs placebo to prevent chronic pain after whiplash injury in at-risk individuals: results of a feasibility study for a large randomised controlled trial. Pain, 163(2), pp.e274-e284. doi: 10.1097/j.pain.0000000000002362

Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes

Wijeratne, T., Kuan, W.S., Kelly, A.M., Chu, K.H., Kinnear, F.B., Keijzers, G., Body, R., Karamercan, M.A., Klim, S., Kamona, S. and Graham, C.A., 2022. Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes. Neuroepidemiology, pp.1-9. DOI https://doi.org/10.1159/000520548

Exploring Cultural and Linguistic Diversity in the Emergency Department (CALD ED) study

Quick facts

Principal investigator:

Dr. Ya-Ling Huang

Team members:

Prof Julia Crilly, Dr Dinesh Palipana, Ms Amy Sweeny, Mr Robert Lee, Dr Ping Zhang, Dr Wietske Blom-Ham, Ms Marina Chand, Professor Cindy Shannon and Dr Shahina Braganza

Project commenced:
2021

Exploring Cultural and Linguistic Diversity in the Emergency Department (CALD ED) study: Phase 1 Quantitative study. Gold Coast Health Collaborative Research Grant Scheme 2021.

This study aims to explore cultural and linguistic diversity (CALD) in the Emergency Department (ED). It is hoped that the outcomes of this study will help inform subsequent research and clinical evidence-based strategies to support research sustainability regarding patients from CALD backgrounds who present to the ED.

Grants Awarded

Gold Coast Health Collaborative Research Grant Scheme
$43,310
Emergency Medicine Foundation
$72,609

ARISE FLUIDS Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In emergency Department Sepsis

Quick facts

Principal investigator:

Prof Gerben Keijzers

Team members:

Dr Katya May, Ms Emma Hall, Dr Richard Pellatt, Dr James Winearls, Dr James McCollough, Ms Mandy Tallot and Ms Maimoonbe Gough

Project commenced:
2021

This study is conducted in collaboration with the Australian and New Zealand Intensive Care Research Centre (ANZIC-RC). It is endorsed by the Australian and New Zealand Intensive Care Society Clinical Trials Group & the Australian College for Emergency Medicine Clinical Trials Network.

The aim of this study is to compare the effect of a strategy of restricted fluids and early introduction of vasopressors to a strategy which involves a larger initial volume of IV fluid and later vasopressor administration if required, for haemodynamic resuscitation of patients with early septic shock.

The objective is to provide robust evidence for clinicians regarding the optimal approach to early haemodynamic resuscitation in septic shock to improve patient-centred clinical outcomes.

Grants Awarded

Medical Research Future Fund
$2,335,540

Clinical presentation and assessment of older patients presenting with headache to emergency departments: A multicentre observational study.

Beck, S., Kinnear, F.B., Maree Kelly, A., Chu, K.H., Sen Kuan, W., Keijzers, G., Body, R., Karamercan, M.A., Klim, S., Wijeratne, T. and Kamona, S., 2021. Clinical presentation and assessment of older patients presenting with headache to emergency departments: A multicentre observational study. Australasian Journal on Ageing.

Comparative and critical analysis of key eligibility criteria for voluntary assisted dying under five legal frameworks.

White, B., Close, E., Willmott, L., Del Villar, K., Downie, J., Cameron, J., Hewitt, J., Meehan, R. and Ley Greaves, L., 2021. Comparative and critical analysis of key eligibility criteria for voluntary assisted dying under five legal frameworks. University of New South Wales Law Journal.

Buddy-up: research reach, adoption, and implementation

Quick facts

Principal investigator:

Dr Eve Purdy

Team members:

Dr Daniel Weston, Dr Charlotte Alexander, Dr Richard Pellatt, Prof Gerben Keijzers, Ms Amy Sweeny, Ms Katie East, Dr Sushma Vytla, Mr Luc Nguyen

The “Buddy Study” funded in the EMF grant round 25 showed a common type of hand fracture can be treated without a plaster – a finding that if applied broadly could result in patients returning to work faster and significant healthcare savings. However, since the study was published in 2019 it is unclear to what degree there has been a change in how clinicians actually treat this fracture.

This follow up study will explore factors related to research reach, adoption, and implementation at two hospitals in Queensland to 1) inform a strategy to implement knowledge related to hand fractures and to 2) explore how participation in research affects implementation.

Grants Awarded

Emergency Medicine Foundation Grants
$11,470

Cellulitis in the emergency department, a prospective management cohort study

Quick facts

Principal investigator:

Dr Rachael Nightingale

Team members:

Dr Peter Snelling, A/Prof Andrew Bulmer, Ms Amy Sweeny, Prof Gerben Keijzers, Dr Richard Pellatt, Dr Eve Purdy, Dr Charlotte Alexander, Dr Nimai Etheridge and Dr Son Nghiem

Cellulitis is an infection of the skin and underlying soft tissues and leads to redness, pain and sometimes fever. Once diagnosed, the emergency doctor needs to decide an appropriate type and dose of antibiotic and decide to give it orally (tables/capsules) or intravenously (via a drip).

Despite this being a common diagnosis in the ED, guidelines are not based on high-quality evidence making it difficult for doctors to make evidence-based choices and there is wide variation in how cellulitis is treated. This prospective cohort management study aims to describe the ED management and clinical outcomes of adult patients with cellulitis.

Grants Awarded

Emergency Medicine Foundation Grants
$39,792
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