Epidemiology, treatment and outcome of patients with lower respiratory tract infection presenting to emergency departments with dyspnoea (AANZDEM and EuroDEM studies).

Rousseau, G., Keijzers, G., van Meer, O., Craig, S., Karamercan, M., Klim, S., Body, R., Kuan, W.S., Harjola, V.P., Jones, P. and Verschuren, F., Epidemiology, treatment and outcome of patients with lower respiratory tract infection presenting to emergency departments with dyspnoea (AANZDEM and EuroDEM studies). Emergency Medicine Australasia.

Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis, a multicentre observational study (ARISE FLUIDS observational study): Rationale, methods and analysis plan.

Keijzers, G., Macdonald, S.P., Udy, A.A., Arendts, G., Bailey, M., Bellomo, R., Blecher, G.E., Burcham, J., Delaney, A., Coggins, A.R. and Fatovich, D.M., 2019. The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In Emergency Department Sepsis, a multicentre observational study (ARISE FLUIDS observational study): Rationale, methods and analysis plan. Emergency Medicine Australasia, 31(1), pp.90-96.

Australasian Resuscitation In Sepsis Evaluation: Fluid or Vasopressors in Emergency Department Sepsis (ARISE:Fluids) Trial.

Quick facts

Principal investigator:
Prof Gerben Keijzers
Team members:
Peake S, Mcdonald S, Delaney A, Keijzers G
Project commenced:
2020

Findings from a Gold Coast Health driven investigation into the use of intravenous fluids in sepsis management in emergency patients will be used as the foundation for a larger, $2.33M randomised controlled trial. 

Sepsis, although not very common, is a serious condition where infection leads to organ dysfunction and possibly death. 

The planned ARISE: Fluids study will explore liberal versus restricted fluid management in patients with septic shock after a large study led by principal investigator Professor Gerben Keijzers showed that there was large variation in how much fluid patients were given.

Grants Awarded

The Medical Research Future Fund (MRFF)
$2,335,540

Watch-house detainee emergency healthcare

Quick facts

Principal investigator:

Prof Julia Crilly

Team members:

A/Prof Ed Heffernan, A/Prof David Green OAM, Dr Cathy Lincoln, A/Prof Josh Byrnes, Sen Sgt Paul Gardiner, Prof Stuart Kinner, Dr Caitlin Brandenburg, Prof Stuart Thomas, Dr Annabel Somerville and A/Prof Peter Davidson

Project commenced:
2020

In the acute phase of police detention, health concerns can emerge for detainees, especially around drug dependence, mental health conditions, and physical injury. In addition are system complexities including crowding.

In the event of an infectious disease outbreak (such as COVID-19), crowded conditions amongst a population with greater underlying burden of disease than the general population creates significant public health and economic concern. Furthermore, access to resources and expertise to manage health concerns in this environment can be challenging, especially in rural areas.

Researchers will interview key stakeholders involved with the care delivery and decision making of detainees, to identify innovative strategies to delivering healthcare in watch-house settings. This research will consider the decision making processes and costs associated with the delivery of healthcare in police watch-houses that may reduce the need for transfer to hospital emergency departments or reduce the potential for deaths in custody.

This research addresses the World Health Organisation’s (WHO) recommendation to understand how evidence-based health services can be provided for those requiring treatment, care and illness prevention whilst in police custody. It also identifies ways in which the need for expensive hospital stays can be minimised.

The expected impact of this research is the capability to identify and inform joined-up approaches so that cost-effective, safe, quality emergency care can be provided to detainees in police watch-house settings.

Grants Awarded

Watch-house detainee emergency healthcare
$92,098

A primer for clinical researchers in the emergency department: Part XI. Inertia before investigation: Pre‐test probability in emergency medicine.

Pellatt, R., Purdy, E. and Keijzers, G., 2020. A primer for clinical researchers in the emergency department: Part XI. Inertia before investigation: Pre‐test probability in emergency medicine. Emergency Medicine Australasia.

Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub‐optimal.

van Meer, O., Keijzers, G., Motiejunaite, J., Klim, S., Capsec, J., Kuan, W., Mcnulty, R., Tan, C., Cowell, D.L., Holdgate, A. and Jain, N., 2020. Get with the guidelines: management of chronic obstructive pulmonary disease in emergency departments in Europe and Australasia is sub‐optimal. Internal Medicine Journal, 50(2), pp.200-208.   

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